Exercise “Non-Responders” Don’t Exist—Here’s Why Your Program Isn’t Paying Off

4 key principles often missing from exercise programs

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Zachary Walston
Jun 17, 2025
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4 key principles often missing from exercise programs

“I’ve tried everything.”

As a physical therapist, I hear this nearly every day. It comes from people frustrated by failed attempts to lose weight, build muscle, or find relief from chronic pain. They’ve cycled through countless programs, diets, and challenges, often putting in weeks or months of effort with little to show for it. Any success they see is usually short-lived.

But have they truly tried everything? Not quite.

I’m not doubting their effort or sincerity. I know most people are doing their best with the tools they’ve been given. What I am challenging is the idea that all possibilities have been exhausted. In reality, most people are stuck repeating slightly different versions of the same flawed strategy. When you start digging into the details—what the program actually looked like, how hard they trained, how much they recovered—it becomes clear there’s still a lot left to try.

This article focuses specifically on exercise. Nutrition plays a huge role too, but that’s a topic for another time. Here, we’re going to break down why the idea of an exercise non-responder is largely a myth, and what really needs to change when training efforts fail.

What exactly is a non-responder?

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